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Welcome to the geneontology GitHub organization!

The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research. For more information, please see our website, http://geneontology.org/.

Overview of some of the key repositories in this organization:

  • geneontology.github.io - GO documentation
  • go-ontology - Source ontology files for the Gene Ontology. This is primarily for the developers of the GO and contains the source code for the GO ontology. To download ontology files, please use the Downloads menu on our website.
  • go-annotation - Issues about GO annotations (manual & automated)
  • go-site - Metadata, tools, and files associated with the Gene Ontology website
  • noctua - Graph-based modeling / editing tools for biology
  • helpdesk - A place for the GO community to ask for help or report issues.

Getting help

If you have general questions about GO, check our Frequently Asked Questions.

If you have a specific question about GO, its data, usage, software, or services, please create a ticket in our discussion tracker.

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  1. helpdesk helpdesk Public

    The Gene Ontology Helpdesk

    16 6

  2. go-announcements go-announcements Public

    Announcements related to ontology changes that may impact groups using GO, such as obsoletions, merges, etc.

    17 1

  3. geneontology.github.io geneontology.github.io Public

    Repository for storing GO documentation, directly available through the general GO site

    SCSS 8 9

  4. go-ontology go-ontology Public

    Source ontology files for the Gene Ontology

    Makefile 255 47

  5. go-annotation go-annotation Public

    This repository hosts the tracker for issues pertaining to GO annotations.

    Python 39 10

  6. go-site go-site Public

    A collection of metadata, tools, and files associated with the Gene Ontology public web presence.

    JavaScript 49 89

Repositories

Showing 10 of 148 repositories
  • noctua-models Public

    This is the data repository for the models created and edited with the Noctua tool stack for GO.

    geneontology/noctua-models's past year of commit activity
    Makefile 13 CC-BY-4.0 3 79 (1 issue needs help) 2 Updated Oct 21, 2026
  • go-ontology Public

    Source ontology files for the Gene Ontology

    geneontology/go-ontology's past year of commit activity
    Makefile 255 CC-BY-4.0 47 664 72 Updated Oct 21, 2026
  • go-cam-drop-box Public

    Staging drop box for GO-CAM model submissions, validated via PR CI. Forming.

    geneontology/go-cam-drop-box's past year of commit activity
    Python 0 10 1 15 Updated Oct 20, 2026
  • go-jupyter Public

    Reproducible JupyterHub-on-EC2 giving each user a Claude Code + JupyterLab account, seeded from a starter template (GO agentic biocuration).

    geneontology/go-jupyter's past year of commit activity
    Shell 1 BSD-3-Clause 0 28 1 Updated Oct 20, 2026
  • go-skills Public

    Agent skills (SKILL.md) for Gene Ontology curation: install with npx skills add geneontology/go-skills

    geneontology/go-skills's past year of commit activity
    Python 0 BSD-3-Clause 1 1 2 Updated Oct 20, 2026
  • geneontology/standard-annotation-backend's past year of commit activity
    Python 0 0 0 0 Updated Oct 20, 2026
  • gocam-py Public

    Draft data model for GO-CAMs

    geneontology/gocam-py's past year of commit activity
    Python 3 BSD-3-Clause 2 13 3 Updated Oct 19, 2026
  • go-site Public

    A collection of metadata, tools, and files associated with the Gene Ontology public web presence.

    geneontology/go-site's past year of commit activity
    JavaScript 49 BSD-3-Clause 89 229 41 Updated Oct 19, 2026
  • amigo3-prototype Public

    Prototype of AmiGO 3, a browser for Gene Ontology annotations, GO-CAMs and modules

    geneontology/amigo3-prototype's past year of commit activity
    Python 1 0 0 0 Updated Oct 19, 2026
  • minerva Public
    geneontology/minerva's past year of commit activity
    Java 11 BSD-3-Clause 10 53 11 Updated Oct 19, 2026